Chamaelirium luteum
Parts used and where grown
False unicorn is native to Mississippi and continues to grow primarily in the southern part of the United States. The roots of false unicorn are most commonly used in herbal medicine.
False unicorn has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
* - Dysmenorrhea (painful menstruation)
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
Parts used and where grown
False unicorn is native to Mississippi and continues to grow primarily in the southern part of the United States. The roots of false unicorn are most commonly used in herbal medicine.
False unicorn has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
* - Dysmenorrhea (painful menstruation)
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Historical or traditional use (may or may not be supported by scientific studies)
The medicinal use of false unicorn root is based in traditional Native American herbalism. It was recommended for many women’s health conditions, including dysmenorrhea (painful menstruation) and other irregularities of menstruation, as well as to prevent miscarriages.1 False unicorn was also used as a remedy for morning sickness.
Active constituents
Steroidal saponins are generally credited with providing false unicorn root’s activity.2 However, modern investigations have not confirmed this, and no research exists about the medical applications of this herb.
How much is usually taken?
False unicorn root tincture, 1/2–1 teaspoon (2–5 ml) three times per day, is sometimes recommended .3 The dried root, 1/4–1/2 teaspoon (1–2 grams) three times per day, is also used.
Are there any side effects or interactions?
No adverse effects have been reported with the use of false unicorn. Although false unicorn has been used historically for nausea and vomiting of pregnancy and to prevent miscarriages, its actions as a possible uterine tonic make its use during pregnancy potentially unsafe.
At the time of writing, there were no well-known drug interactions with false unicorn.
Historical or traditional use (may or may not be supported by scientific studies)
The medicinal use of false unicorn root is based in traditional Native American herbalism. It was recommended for many women’s health conditions, including dysmenorrhea (painful menstruation) and other irregularities of menstruation, as well as to prevent miscarriages.1 False unicorn was also used as a remedy for morning sickness.
Active constituents
Steroidal saponins are generally credited with providing false unicorn root’s activity.2 However, modern investigations have not confirmed this, and no research exists about the medical applications of this herb.
How much is usually taken?
False unicorn root tincture, 1/2–1 teaspoon (2–5 ml) three times per day, is sometimes recommended .3 The dried root, 1/4–1/2 teaspoon (1–2 grams) three times per day, is also used.
Are there any side effects or interactions?
No adverse effects have been reported with the use of false unicorn. Although false unicorn has been used historically for nausea and vomiting of pregnancy and to prevent miscarriages, its actions as a possible uterine tonic make its use during pregnancy potentially unsafe.
At the time of writing, there were no well-known drug interactions with false unicorn.

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