Herbal Remedies & Vitamin Guide

04 May 2007

willow

Common name
Willow bark
Botanical name
Salix alba
Parts used and where grown
The willow tree grows primarily in central and southern Europe, although it is also found in North America. The bark is used to make herbal extracts.

Willow has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
** - Low back pain
** - Osteoarthritis
* - Bursitis
* - Fever
* - Pain
* - Rheumatoid arthritis
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Historical or traditional use (may or may not be supported by scientific studies)
Willow bark was used traditionally by herbalists for fever, headache,
pain, and rheumatic complaints.1 In the late 19th century, the constituent salicylic acid was isolated from willow bark and went on to become the model for the development of aspirin (acetylsalicylic acid).2
Active constituents
The glycoside salicin, from which the body can split off salicylic acid, is thought to be the source of the anti-inflammatory and pain-relieving actions of willow.3 The analgesic actions of willow are typically slow to develop but may last longer than the effects of standard aspirin products. One trial has found that a combination herbal product including 100 mg willow bark taken for two months improved functioning via pain relief in people with
osteoarthritis.4 Another trial found that 1360 mg of willow bark extract per day (delivering 240 mg of salicin) for two weeks was somewhat effective in treating pain associated with knee and/or hip osteoarthritis.5 Use of high amounts of willow bark extract may also help people with low back pain. One four-week trial found 240 mg of salicin from a willow extract was effective in reducing exacerbations of low back pain.6
How much is usually taken?
Willow extracts standardized for salicin content are available. The commonly recommended intake of salicin has been 60–120 mg per day.7 However, newer studies suggest a higher salicin intake of 240 mg per day may be more effective for treating pain.8 A willow tea can be prepared from 1/4–1/2 teaspoon (1–2 grams) of bark boiled in about 7 ounces (200 ml) of water for ten minutes. Five or more cups (1250 ml) of this tea can be drunk per day. Tincture, 1–1 1/2 teaspoons (5–8 ml) three times per day, is also occasionally used.

Are there any side effects or interactions?
As with aspirin, some people may experience stomach upset from taking willow. Although such symptoms are less likely from willow than from
aspirin, people with ulcers and gastritis should, nevertheless, avoid this herb.9 Again, as with aspirin, willow should not be used to treat fevers in children since it may cause Reye’s syndrome.
Drug Interactions
Certain medicines interact with
willow: Some interactions may increase the need for willow (+), other interactions may be negative (-) and indicate willow should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the
Medicines index.
Bismuth Subsalicylate (-)
Celecoxib (-)
Diclofenac (-)
Etodolac (-)
Flurbiprofen (-)
Ibuprofen (-)
Indomethacin (-)
Ketoprofen (-)
Ketorolac (-)
Live Influenza Vaccine+C2461 Intranasal (-)
Metoclopramide (+)
Nabumetone (-)
Nadolol (-)
Naproxen/Naproxen Sodium (-)
Nonsteroidal Anti-Inflammatory Drugs (-)
Oxaprozin (-)
Piroxicam (?)
Repaglinide (-)
Salsalate (-)
Sulindac (-)
Ticlopidine (-)
Zafirlukast (-)

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