Wild clover
Botanical name
Botanical name
Trifolium pratense
Parts used and where grown
This plant grows in Europe and North America. The flowering tops are used in botanical medicine. Another plant, white clover, grows in similar areas. Both have white arrow-shaped patterns on their leaves.
Red clover has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
** - Menopause
** - Osteoporosis
* - Cough
* - Eczema
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
Parts used and where grown
This plant grows in Europe and North America. The flowering tops are used in botanical medicine. Another plant, white clover, grows in similar areas. Both have white arrow-shaped patterns on their leaves.
Red clover has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
** - Menopause
** - Osteoporosis
* - Cough
* - Eczema
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Historical or traditional use (may or may not be supported by scientific studies)
Traditional Chinese Medicine and Western folk medicine used this plant as a diuretic, a cough expectorant (an agent that promotes discharge of mucus from the respiratory passages), and an alterative.1 Alterative plants were considered beneficial for chronic conditions, particularly those afflicting the skin.
Active constituents
Red clover is known as an alterative agent (i.e., one that produces gradual beneficial changes in the body, usually by improving nutrition; also known as a “blood cleanser”). It is a traditional remedy for psoriasis and eczema. However, the mechanism of action and constituents responsible for red clover’s purported benefit in skin conditions are unknown. Modern research has revealed that red clover also contains high amounts of isoflavones, such as genistein, which have weak estrogen-like properties.2 Modern research has focused on a red clover extract high in isoflavones as a possible treatment for symptoms associated with menopause and cardiovascular health in menopausal women. In a double-blind study, administration of 80 mg of isoflavones per day from red clover reduced the frequency of hot flashes in postmenopausal women. The benefit was noticeable after 4 weeks of treatment and became more pronounced after a total of 12 weeks.3 Another double-blind trial found that red clover improved cardiovascular function in menopausal women,4 Various laboratory studies and one case report of a man with prostate cancer suggest red clover isoflavones may help prevent cancer.5 6 In another case study, use of red clover by a man with prostate cancer led to noticeable anticancer effects in his prostate after the cancer was surgically removed. Although the isoflavones in red clover may help prevent certain forms of cancer (e.g., breast and prostate), further studies are needed before red clover is recommended for cancer patients.
How much is usually taken?
Traditionally, red clover is taken as a tea, by adding 1 cup (250 ml) of boiling water to 2–3 teaspoons (10–15 grams) of dried flowers and steeping, covered, for ten to fifteen minutes.7 Three cups (750 ml) can be drunk each day. Red clover can also be used in capsule or tablet form, equivalent to 2–4 grams of the dried flowers. Also, 1/2–3/4 teaspoon (2–4 ml) of tincture three times per day may be taken. Standardized extracts providing 40 mg isoflavones per day are available as well.8
Are there any side effects or interactions?
Non-fermented red clover is relatively safe. However, fermented red clover may cause bleeding and should be avoided. Red clover supplements should be avoided by pregnant or breast-feeding women and their safety has not been established in young children and infants.
Historical or traditional use (may or may not be supported by scientific studies)
Traditional Chinese Medicine and Western folk medicine used this plant as a diuretic, a cough expectorant (an agent that promotes discharge of mucus from the respiratory passages), and an alterative.1 Alterative plants were considered beneficial for chronic conditions, particularly those afflicting the skin.
Active constituents
Red clover is known as an alterative agent (i.e., one that produces gradual beneficial changes in the body, usually by improving nutrition; also known as a “blood cleanser”). It is a traditional remedy for psoriasis and eczema. However, the mechanism of action and constituents responsible for red clover’s purported benefit in skin conditions are unknown. Modern research has revealed that red clover also contains high amounts of isoflavones, such as genistein, which have weak estrogen-like properties.2 Modern research has focused on a red clover extract high in isoflavones as a possible treatment for symptoms associated with menopause and cardiovascular health in menopausal women. In a double-blind study, administration of 80 mg of isoflavones per day from red clover reduced the frequency of hot flashes in postmenopausal women. The benefit was noticeable after 4 weeks of treatment and became more pronounced after a total of 12 weeks.3 Another double-blind trial found that red clover improved cardiovascular function in menopausal women,4 Various laboratory studies and one case report of a man with prostate cancer suggest red clover isoflavones may help prevent cancer.5 6 In another case study, use of red clover by a man with prostate cancer led to noticeable anticancer effects in his prostate after the cancer was surgically removed. Although the isoflavones in red clover may help prevent certain forms of cancer (e.g., breast and prostate), further studies are needed before red clover is recommended for cancer patients.
How much is usually taken?
Traditionally, red clover is taken as a tea, by adding 1 cup (250 ml) of boiling water to 2–3 teaspoons (10–15 grams) of dried flowers and steeping, covered, for ten to fifteen minutes.7 Three cups (750 ml) can be drunk each day. Red clover can also be used in capsule or tablet form, equivalent to 2–4 grams of the dried flowers. Also, 1/2–3/4 teaspoon (2–4 ml) of tincture three times per day may be taken. Standardized extracts providing 40 mg isoflavones per day are available as well.8
Are there any side effects or interactions?
Non-fermented red clover is relatively safe. However, fermented red clover may cause bleeding and should be avoided. Red clover supplements should be avoided by pregnant or breast-feeding women and their safety has not been established in young children and infants.
Drug Interactions
Certain medicines interact with red clover: Some interactions may increase the need for red clover (+), other interactions may be negative (-) and indicate red clover should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines index.
Estrogens (Combined) (-)
Heparin (-)
Ticlopidine (-)
Warfarin (-)
Certain medicines interact with red clover: Some interactions may increase the need for red clover (+), other interactions may be negative (-) and indicate red clover should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines index.
Estrogens (Combined) (-)
Heparin (-)
Ticlopidine (-)
Warfarin (-)
Source: www.cncahealth.com

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