Herbal Remedies & Vitamin Guide

24 April 2007

lysine

Introduction
Lysine is an essential amino acid needed for growth and to help maintain nitrogen balance in the body. (Essential amino acids cannot be made in the body and must be supplied by the diet or supplements.)
Where is it found?
Brewer’s yeast, legumes, dairy, fish, and meat all contain significant amounts of lysine.
Lysine has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
*** - Cold sores (recurrence prevention)
** - Genital Herpes
* - Shingles
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Who is likely to be deficient?
Most people, including vegans (
vegetarians who also avoid dairy and eggs), consume adequate amounts of lysine. However, vegans whose diets contain large amounts of grains and only minimal amounts of beans could become deficient in lysine. Athletes involved in frequent vigorous exercise have increased need for essential amino acids, although most diets meet these increased needs. The essential amino acid requirements of burn patients may exceed the amount of lysine in the diet.
How much is usually taken?
Most people do not require lysine supplementation. Doctors often suggest that people with recurrent
herpes simplex infections take 1,000–3,000 mg of lysine per day.
Are there any side effects or interactions?
In animals, high amounts of lysine have been linked to increased risk of
gallstones1 and elevated cholesterol.2 At supplemental amounts, no consistent problems have been reported in humans, though abdominal cramps and transient diarrhea have occasionally been reported at very high (15–40 grams per day) intakes.3
Lysine supplementation increases the absorption of
calcium and may reduce its excretion.4 As a result, some researchers believe that lysine may eventually be shown to have a role in the prevention and treatment of osteoporosis.5
Lysine works with other essential
amino acids to maintain growth, lean body mass, and the body’s store of nitrogen.
At the time of writing, there were no well-known drug interactions with lysine.

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