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L-tyrosine is a nonessential amino acid (protein building block) that the body synthesizes from phenylalanine, another amino acid. Tyrosine is important to the structure of almost all proteins in the body. It is also the precursor of several neurotransmitters, including L-dopa, dopamine, norepinephrine, and epinephrine.
Where is it found?
Dairy products, meats, fish, wheat, oats, and most other protein-containing foods contain tyrosine.
L-tyrosine has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
*** - Stress
** - Depression
** - Phenylketonuria (for deficiency)
* - Alcohol withdrawal support
* - Parkinson’s disease
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
Where is it found?
Dairy products, meats, fish, wheat, oats, and most other protein-containing foods contain tyrosine.
L-tyrosine has been used in connection with the following conditions (refer to the individual health concern for complete information):
Science Ratings - Health Concerns
*** - Stress
** - Depression
** - Phenylketonuria (for deficiency)
* - Alcohol withdrawal support
* - Parkinson’s disease
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Who is likely to be deficient?
Some people affected by PKU are deficient in tyrosine. Tyrosine levels are occasionally low in depressed people.1 Any person losing large amounts of protein, such as those with some kidney diseases, may be deficient in several amino acids, including tyrosine.2
How much is usually taken?
Most people should not supplement with L-tyrosine. Some human research with people suffering from a variety of conditions used 100 mg per 2.2 pounds of body weight, equivalent to about 7 grams per day for an average-sized person. The appropriate amount to use in people with PKU is not known, therefore, the monitoring of blood levels by a physician is recommended.
Are there any side effects or interactions?
L-tyrosine has not been reported to cause any serious side effects. However, it is not known whether long-term use of L-tyrosine, particularly in large amounts (such as more than 1,000 mg per day) is safe. For that reason, long-term use of L-tyrosine should be monitored by a doctor.
Vitamin B6, folic acid, and copper are necessary for conversion of L-tyrosine into neurotransmitters.
Who is likely to be deficient?
Some people affected by PKU are deficient in tyrosine. Tyrosine levels are occasionally low in depressed people.1 Any person losing large amounts of protein, such as those with some kidney diseases, may be deficient in several amino acids, including tyrosine.2
How much is usually taken?
Most people should not supplement with L-tyrosine. Some human research with people suffering from a variety of conditions used 100 mg per 2.2 pounds of body weight, equivalent to about 7 grams per day for an average-sized person. The appropriate amount to use in people with PKU is not known, therefore, the monitoring of blood levels by a physician is recommended.
Are there any side effects or interactions?
L-tyrosine has not been reported to cause any serious side effects. However, it is not known whether long-term use of L-tyrosine, particularly in large amounts (such as more than 1,000 mg per day) is safe. For that reason, long-term use of L-tyrosine should be monitored by a doctor.
Vitamin B6, folic acid, and copper are necessary for conversion of L-tyrosine into neurotransmitters.
Drug Interactions
Certain medicines interact with L-tyrosine: Some interactions may increase the need for L-tyrosine (+), other interactions may be negative (-) and indicate L-tyrosine should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines index.
Mixed Amphetamines (+)
Certain medicines interact with L-tyrosine: Some interactions may increase the need for L-tyrosine (+), other interactions may be negative (-) and indicate L-tyrosine should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines index.
Mixed Amphetamines (+)
Source: www.cncahealth.com
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